Blood group O may be protective against and blood group A may render patients more susceptible to, respiratory failure in Covid-19 infection

During the peak of hospitalizations of patients with severe Covid-19 in Italy and Spain in March, a group of researchers in these and other countries obtained and analyzed samples, resulting in the identification of two chromosomal loci with Covid-19–induced respiratory failure. The findings confirm potential involvement of the ABO blood-group system

In this group of patient studied, a blood-group–specific analysis showed a higher risk of severe disease complication (respiratory failure) in blood group A than in other blood groups and a protective effect in blood group O as compared with other blood groups.

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